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Updated: Jun 14, 2026

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Laparoscopic Duodenum-Preserving Pancreatic Head Resection via Inferior Infracolic Approach: A Surgical Approach for Benign Lesions
Published on: February 9, 2024
Clinical Outcomes of Duodenum-Preserving Core Pancreatic Head Resection (DP-CoPHR)
Shilin Guo1, Shuhai Chen, Han Liu
1Department of Pancreatic Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Summary
Laparoscopic duodenum-preserving core pancreatic head resection (DP-CoPHR) is a viable option for select pancreatic head tumors. While complications like pancreatic fistula occurred, the procedure showed no perioperative mortality.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Duodenum-preserving pancreatic head resection (DPPHR) offers advantages over pancreaticoduodenectomy for specific pancreatic head tumors.
- DPPHR is technically challenging, necessitating procedural modifications.
- A novel technique, duodenum-preserving core pancreatic head resection (DP-CoPHR), was developed to simplify the procedure.
Purpose of the Study:
- To evaluate the clinical outcomes of the modified laparoscopic DP-CoPHR technique.
- To assess the feasibility and safety of DP-CoPHR for benign or low-grade malignant tumors in the pancreatic head core region.
Main Methods:
- Retrospective analysis of 6 patients undergoing laparoscopic DP-CoPHR.
- Inclusion criteria: benign or low-grade malignant tumors in the pancreatic head core region.
- Data collected included operative time, blood loss, complications, and hospital stay.
Main Results:
- Successful completion of laparoscopic DP-CoPHR in all 6 patients.
- Tumor types included solid pseudopapillary neoplasm, serous cystic neoplasm, and IPMN.
- Median operative time: 267.5 minutes; median blood loss: 100 mL; median hospital stay: 11.5 days.
- Postoperative complications: 50% pancreatic fistula (grade B), 1 patient with biliary fistula (managed with ERBD).
- No perioperative mortality or reoperations observed.
Conclusions:
- Laparoscopic DP-CoPHR is a feasible alternative for selected patients with pancreatic head tumors.
- Further long-term follow-up is necessary to assess the patency of the common bile duct.
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