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Resectability redefined: Lessons from quadruple therapy in HCC
1Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Med (New York, N.Y.)
|June 12, 2026
Abstract:
Qiu et al. report a phase II trial (PLATIC) evaluating sintilimab, lenvatinib, and transarterial chemoembolization combined with hepatic arterial infusion chemotherapy (TACE-HAIC) as conversion therapy for unresectable hepatocellular carcinoma (uHCC).1 While these results represent a substantial advance in conversion therapy, they also raise critical questions about how to optimally integrate locoregional and systemic therapies.