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Dual-target CAR-T cell therapy: latest updates from the 2025 ASH annual meeting

Shi Feng1, Ran Kong1, Li Xiao2

  • 1Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jingwu Road, Jinan, 250021, Shandong, China.

Experimental Hematology & Oncology
|June 13, 2026
PubMed
Summary

Dual-target CAR-T cell therapy shows promise for overcoming limitations of single-target approaches. Advancements in engineering and preclinical data suggest improved disease control in various cancers and autoimmune diseases.

Keywords:
Cellular therapyDual-target CAR-THematological malignancies

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