Related Experiment Video

Updated: Jun 16, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
06:14

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

Effect of concomitant rifampin and clarithromycin on elexacaftor-tezacaftor-ivacaftor using a physiologically based

Madeline Sanders1, Eunjin Hong2, Manya Jain1

  • 1Department of Clinical Pharmacy, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA.

Expert Opinion on Drug Metabolism & Toxicology
|June 13, 2026
PubMed
Abstract

Keywords:
CYP3ACystic fibrosisdrug-drug interactionselexacaftor/tezacaftor/ivacaftorphysiologically based pharmacokineticsrifampin

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