Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Signal Flow Graphs01:18

Signal Flow Graphs

Signal-flow graphs offer a streamlined and intuitive approach to representing control systems, providing an alternative to traditional block diagrams. These graphs use branches to symbolize systems and nodes to represent signals, effectively illustrating the relationships and interactions within the system.
In a signal-flow graph, branches denote the system's transfer functions, while nodes represent the signals. The direction of signal flow is indicated by arrows, with the corresponding...
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is also...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hearing outcomes after cochlear implantation in two patients with ATP6V1B2-related deafness and onychodystrophy.

European journal of medical genetics·2026
Same author

Pediatric Cochlear Implant Outcomes in Auditory Neuropathy, Cochlear Nerve Deficiency, and Sensorineural Hearing Loss: An 8-Year Longitudinal Study.

Ear and hearing·2026
Same author

Evaluation of Graph-Based Algorithms for Early Detection of In-Hospital Mortality.

Studies in health technology and informatics·2026
Same author

Investigating the analytical robustness of the social and behavioural sciences.

Nature·2026
Same author

School participation in autistic girls and boys: The role of social-communication abilities and extrinsic barriers.

Autism : the international journal of research and practice·2026
Same author

Validation of visual analogue scales to assess occupational stress compared to the Karasek questionnaire: A cross sectional study.

PloS one·2026
Same journal

A conserved pulvinar projection to the amygdala revealed in macaque monkeys (Macaca mulatta).

Brain structure & function·2026
Same journal

Cerebellar pathway diffusion MRI measures are linked to core autism symptoms in early adolescents aged 9 to 11 years.

Brain structure & function·2026
Same journal

The role of the subcortical structures in subthreshold depression: evidence from static and dynamic functional connectivity.

Brain structure & function·2026
Same journal

Auditory conditioned fear elicits anxiety-like behavior and differential neuronal remodeling in the prelimbic and infralimbic cortex of rats.

Brain structure & function·2026
Same journal

Brain structure and function in Homo naledi.

Brain structure & function·2026
Same journal

Ultrastructural response of the retinal cells and neurovascular unit to neuroinflammation induced by lipopolysaccharide.

Brain structure & function·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Structure-function dynamics in healthy cognitive aging: a graph signal processing approach.

Clément Guichet1, Sophie Achard2, Martial Mermillod1

  • 1Univ. Grenoble Alpes, CNRS LPNC UMR 5105, 1251 Avenue Centrale, 38000, Grenoble Cedex 09, France.

Brain Structure & Function
|June 13, 2026
PubMed
Summary
This summary is machine-generated.

Healthy brain aging involves shifts in how structure and function connect. Sensorimotor integration helps maintain cognitive control and semantic skills, especially into older adulthood.

Keywords:
Cognitive agingFunctional connectivityGraph signal processingLifespanStructural connectivity

More Related Videos

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Related Experiment Videos

Last Updated: Jun 16, 2026

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Network Science

Background:

  • Network neuroscience studies brain connectivity changes in aging.
  • Limited studies integrate structural, functional, and cognitive data across the lifespan.

Purpose of the Study:

  • Investigate how structural connectivity constrains functional brain signals across the adult lifespan.
  • Examine age-related changes in structure-function relationships within cognitive systems.

Main Methods:

  • Analyzed resting-state fMRI and diffusion-weighted imaging data from 597 healthy adults (ages 18-88) from the CamCAN dataset.
  • Applied a graph signal processing framework to assess structure-function coupling.

Main Results:

  • Identified distinct age-related reorganization patterns in control and semantic cognitive systems.
  • Found that structurally-coupled sensorimotor integration supports cognitive control until midlife.
  • Observed sensorimotor integration aiding semantic processing and lexical skills in older adults.

Conclusions:

  • Sensory-driven processes reconfigure the aging brain to support semantic cognition.
  • Midlife may involve a shift in brain integrative processing.
  • Structure-function coupling dynamics are crucial for understanding healthy neurocognitive aging.