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Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Voluntary micronutrient interventions save lives: Evidence from China's free folic acid supplementation policy
Chang Liu1, Ruiming Liu1, Yuan Xu2
1National Academy of Development and Strategy, Renmin University of China, No. 59 Zhongguancun Street, Beijing, 100872, China.
Abstract:
This study assesses the health impacts of a voluntary micronutrient intervention by examining China's Free Folic Acid Supplementation Program (FFASP), a nationwide policy offering free supplements to rural women planning pregnancies since 2008. Using a difference-in-differences design, we estimate that FFASP reduced infant mortality by approximately 2.8%, accounting for 11.7% of the observed narrowing in rural-urban disparities during the intervention period. A cost-benefit analysis indicates that the program averted deaths at $15,552 per life saved, a figure markedly lower than Chinese and global value-of-statistical-life benchmarks. Mortality reductions were most pronounced among female infants and driven by declines in folate deficiency-related complications such as birth defects and low birthweight. Program efficacy was strongest in regions with higher compliance, greater pre-intervention prevalence of neural tube defects, and lower educational attainment. These findings demonstrate that well-targeted voluntary micronutrient interventions can yield significant mortality reductions in resource-limited settings, challenging skepticism toward non-mandatory intervention programs.
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