Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
Dose Size and Dosing Frequency: Determination Methods01:21

Dose Size and Dosing Frequency: Determination Methods

Determining the optimal dose size and dosing frequency in pharmacotherapy is crucial for achieving therapeutic effectiveness while minimizing adverse effects. This article explores the methodologies employed in determining these parameters, focusing on their significance and interplay to tailor dosing regimens.Dose Size: Dose size refers to the amount of a drug administered in a single dose. It is determined based on the drug's pharmacodynamics and pharmacokinetics properties and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Special Issue on Sustainability.

Journal of medical imaging and radiation oncology·2026
Same author

Version upgrades in treatment planning Systems affect clinical application of a multi-Centre knowledge-based planning model.

Technical innovations & patient support in radiation oncology·2026
Same author

Survey evidence demands professional guidance on large language model use in medical physics.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2026
Same author

European Multicentre Study on Recurrent Imaging Practice in Computed Tomography.

The British journal of radiology·2026
Same author

Variant classification for mucopolysaccharidosis type I; ACMG/AMP specification for IDUA from the ClinGen lysosomal diseases variant curation expert panel.

Molecular genetics and metabolism·2026
Same author

Long-term outcomes of stereotactic ablative body radiotherapy for primary kidney cancer (TROG 15.03 FASTRACK II): a multicentre, non-randomised, phase 2 study.

The Lancet. Oncology·2026
Same journal

Highly Variable, Complex, and Contextual: The Business of Radiation Oncology Practice.

International journal of radiation oncology, biology, physics·2026
Same journal

Corrigendum to 'Radiation Therapy Promotes Hepatocellular Carcinoma Immune Cloaking via PD-L1 Upregulation Induced by cGAS-STING Activation' [International Journal of Radiation Oncology*Biology*Physics Volume 112, Issue 5, 1 April 2022, Pages 1243-1255].

International journal of radiation oncology, biology, physics·2026
Same journal

Multicenter external validation of normal tissue complication probability models for radiation-induced primary hypothyroidism in head and neck cancer survivors with long-term endocrine outcomes.

International journal of radiation oncology, biology, physics·2026
Same journal

THGEM-Based Air Ionization Chamber for Online Dose Monitoring in Conventional and FLASH Radiotherapy.

International journal of radiation oncology, biology, physics·2026
Same journal

Single Percussive Ventilation Breath-hold Imaging and Delivery in Lung Tumor Stereotactic Ablative Radiation Therapy: Initial Observations From a Prospective Clinical Trial.

International journal of radiation oncology, biology, physics·2026
Same journal

Proton beam therapy in nonmetastatic rhabdomyosarcoma: Outcome, prognostic factors and the effect of timing of radiation therapy.

International journal of radiation oncology, biology, physics·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Benchmarking Doses to Inform Optimization of Radiological Protection for Verification Imaging in Radiation Therapy.

Colin J Martin1, Sebastien Gros2, Tomas Kron3

  • 1Department of Clinical Physics and Bio-Engineering, University of Glasgow, Gartnavel Royal Hospital, Glasgow, United Kingdom.

International Journal of Radiation Oncology, Biology, Physics
|June 13, 2026
PubMed
Summary
This summary is machine-generated.

Accurate radiation therapy targeting requires frequent imaging, potentially increasing secondary cancer risks. This study proposes applying diagnostic radiology

More Related Videos

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

Related Experiment Videos

Last Updated: Jun 16, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

Area of Science:

  • Medical Physics
  • Radiotherapy
  • Radiation Protection

Background:

  • Accurate targeting in external beam radiation therapy relies on frequent patient imaging.
  • Verification imaging, such as Cone Beam Computed Tomography (CBCT), can expose healthy tissues to additional radiation.
  • Repeated imaging doses, though lower than therapeutic doses, pose a risk of secondary cancers, especially in younger patients.

Purpose of the Study:

  • To review methods for managing patient imaging doses in diagnostic radiology.
  • To explore the application of these methods to optimize radiological protection in image-guided radiotherapy (IGRT).
  • To identify suitable dose quantities for surveying and benchmarking imaging doses in radiotherapy.

Main Methods:

  • Review of dose management strategies in diagnostic radiology.
  • Identification of relevant dose indices like Cone Beam Dose Index (CBDI) and CTDIw for radiotherapy imaging.
  • Discussion of actions needed for dose optimization and establishing radiotherapy-specific dose reference levels.

Main Results:

  • Radiotherapy departments often use default imaging protocols with limited optimization, unlike diagnostic radiology.
  • Information on CBCT imaging doses is frequently unavailable, hindering dose management.
  • Diagnostic radiology practices offer a model for surveying and benchmarking patient imaging doses in IGRT.

Conclusions:

  • Establishing radiotherapy-specific dose reference levels is crucial for optimizing patient doses.
  • Implementing dose optimization can balance image quality with patient safety.
  • Systematic dose reduction through benchmarking can improve the safety and effectiveness of IGRT.