Related Experiment Video
Updated: Jun 16, 2026

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
Neurodegenerative decline following a mild traumatic brain injury: a case report
Melanie A Mason1, James Geiselman2, Shawn Spooner3
1Department of Health and Movement Science, Graceland University, Lamoni, IA, USA. mason6@graceland.edu.
Background:
A growing body of research suggests that mild traumatic brain injury (mTBI) increases the chance of developing neurodegenerative disease in adults. Elderly patients are of great concern due to an increased risk of head injury due to falls.
Case Report:
The patient was a 71-year-old White, non-Hispanic female who fell from a ladder and suffered an initially undiagnosed mild traumatic brain injury (mTBI). Seventeen months after injury, she was evaluated by a concussion specialist who retrospectively diagnosed mTBI. Subsequent neuropsychological evaluation resulted in a diagnosis of probable Lewy body dementia. The patient experienced rapid neurological decline and died thirty-three months after the initial fall.
Conclusions:
Mild traumatic brain injury (mTBI) and its persisting symptoms are frequently misdiagnosed, often leading to symptom-based overmedication and lack of appropriate targeted treatment. This highlights the need for advanced training for providers on mTBI and the potential for persisting symptoms associated with it. Providers also need to understand the risk of neurological decline following mTBI, especially in the elderly population. Clinicians should not rely exclusively on patient self-report for diagnosis and treatment of mTBI and should use a multidisciplinary approach. In addition, disparities in rural access to specialized care must be addressed to ensure equitable post-injury outcomes.
More Related Videos
08:27Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025
09:49Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023