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Proline Ring-Inversion Dynamics in Peptides Enable Cross-Relaxation-Based Dynamic Nuclear Polarization

Florian Taube1, Max Gierth1, Georg Künze2,3,4

  • 1Institute of Chemistry and Department Life, Light & Matter, University Rostock, Rostock, Germany.

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
|June 14, 2026
PubMed
Summary

Specific cross-relaxation enhancement by active motions under DNP (SCREAM-DNP) was investigated in proline-containing peptides. Local structure significantly impacts proline dynamics and SCREAM-DNP efficiency, offering insights for structural biology applications.

Keywords:
SCREAM‐DNPamino acidsprolinepuckering dynamics

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