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Updated: Jun 16, 2026
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Published on: May 10, 2024
The Effect of Closed Incision Negative Pressure Wound Therapy for Prophylactic Use of Postoperative Deep Sternal
Koji Tsutsumi1, Nozomi Yamanaka1, Misato Tokioka1
1Department of Cardiovascular Surgery, National Defense Medical College, Tokorozawa, Saitama, Japan.
Purpose:
The aim of this study was to evaluate the effectiveness of closed-incision negative pressure wound therapy (ciNPWT) as a prophylactic measure to prevent deep sternal wound infection (DSWI) after surgery.
Methods:
A total of 209 patients undergoing isolated coronary artery bypass grafting via median sternotomy were enrolled. The patients were divided into 3 groups according to incisional care. In Group A (n = 63), the wound was covered with sterile gauze dressings alone. In Group B (n = 71), an indwelling subcutaneous drain was placed and the wound was covered with a hydrocolloid dressing. In Group C (n = 75), an indwelling subcutaneous drain was placed and the wound was covered with a ciNPWT device (PICO; Smith & Nephew). The incidence of DSWI occurring within 60 postoperative days was compared among the 3 groups.
Results:
There were no significant differences in preoperative, operative, or postoperative variables among the groups. Postoperative DSWI occurred in 11.1% (7/63) of patients in Group A and 5.6% (4/71) of patients in Group B, whereas no patients in Group C developed DSWI.
Conclusions:
Immediate application of NPWT was associated with a reduced rate of wound infection. This treatment may represent an effective preventive strategy.
