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Updated: Jun 16, 2026

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
Published on: September 18, 2020
Altered knee joint loading in patients with chronic ankle instability during running
Hyung Gyu Jeon1, Kyeongtak Song2, Eun Ji Hong1
1Department of Kinesiology, Yonsei University, Seoul, 03722, Republic of Korea.
Chronic ankle instability (CAI) increases knee joint loading during running, primarily due to quadriceps muscle activity. This highlights the link between ankle and knee health, suggesting targeted rehabilitation for better outcomes.
Area of Science:
- Biomechanics
- Orthopedics
- Sports Medicine
Background:
- Chronic ankle instability (CAI) alters lower extremity biomechanics, potentially increasing joint loading.
- Understanding these biomechanical changes is crucial for detecting early degenerative joint disease.
Purpose of the Study:
- To compare knee joint contact forces (JCF) during running in individuals with CAI versus healthy controls.
- To identify lower extremity muscles contributing to these forces in CAI.
Main Methods:
- Musculoskeletal simulation used to estimate tibiofemoral joint forces (compressive, shear) during running.
- Analysis included muscle contributions and ground reaction forces (GRF).
- Statistical parametric mapping and independent t-tests were applied.
Main Results:
- Individuals with CAI exhibited greater posterior and medial knee shear forces during running compared to controls.
- Compressive impulse was significantly higher in the CAI group, though peak compressive force did not differ.
- Increased knee JCF in CAI was predominantly driven by enhanced quadriceps muscle activity.
Conclusions:
- Greater knee joint loading in CAI is linked to increased quadriceps muscle contributions.
- Findings emphasize the biomechanical connection between ankle and knee joint health.
- Rehabilitation focusing on proximal muscle coordination may mitigate knee joint loading in CAI patients.
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