Testing rates and outcomes in Clostridioides difficile infection between REM (racially and ethnically minoritized)...

Area of Science:

• Infectious Diseases
• Health Disparities
• Clinical Outcomes Research

Background:

• Racial and ethnic disparities in Clostridioides difficile infection (CDI) outcomes are documented but not well understood.
• Previous research indicates potential inequities in CDI diagnosis and treatment.
• Understanding these disparities is crucial for improving patient care and health equity.

Purpose of the Study:

• To investigate racial and ethnic disparities in Clostridioides difficile infection testing rates and clinical outcomes.
• To compare CDI outcomes between racially and ethnically minoritized (REM) patients and non-minoritized patients.
• To identify potential factors contributing to observed disparities in CDI care.

Main Methods:

• Retrospective cohort study design.
• Analysis of patient data from a major academic hospital.
• Comparison of Clostridioides difficile testing rates and key clinical outcomes (e.g., mortality, readmission) between REM and non-minoritized patient groups.

Main Results:

• Testing rates for Clostridioides difficile infection were lower among racially and ethnically minoritized patients.
• Despite lower testing rates, important clinical outcomes did not significantly differ between REM and non-minoritized patients.
• This suggests that while diagnostic access may be unequal, the severity or progression of CDI might not be disproportionately affected in this specific healthcare setting.

Conclusions:

• While disparities in Clostridioides difficile testing exist, this study did not find corresponding differences in major clinical outcomes.
• Further research is needed to explore the reasons behind lower testing rates in minoritized populations and to confirm these findings in diverse healthcare systems.
• Efforts to ensure equitable diagnostic testing for CDI should be considered to address potential underlying systemic issues.