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Lansoprazole-Induced Microscopic Colitis Mimicking Anticancer Drug-Related Diarrhea During Lenvatinib and
Shinichi Maruyama1,2, Takuro Hirano3, Kazuhiro Fuchinoue4
1Department of Pharmacy Saiseikai Yokohamashi Tobu Hospital Yokohama City Kanagawa Japan.
Abstract:
Persistent diarrhea during anticancer therapy may not be attributable to anticancer agents. Our patient presented with diarrhea during lenvatinib-pembrolizumab therapy, likely caused by lansoprazole-induced microscopic colitis. Even when symptoms closely resemble anticancer drug or immune-related colitis, drug-induced colitis due to concomitant medications, including proton pump inhibitors, should be considered.
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