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Neuro-skeletal units and Smart Analgesia: reprogramming sensory neurons for fracture repair

Long Bai1,2,3,4, Jia-Can Su1,2,3,5

  • 1Organoid Research Center, Institute of Translational Medicine, Shanghai University, Shanghai 200444, China.

Military Medical Research
|June 15, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Fibroblast growth factor 9 (FGF9)Fracture repairPain plasticitySensory neuronsSmart Analgesia

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Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...