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Updated: Jun 16, 2026

Analytical Techniques for Assaying Nitric Oxide Bioactivity
Published on: June 18, 2012
Evaluation of Salivary Nitric Oxide Levels in Odontogenic Lesions
Suhair Cherukunnummal1, Tps Gopinath2, S Naresh3
1MBBS Student, KS Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, Deralakatte, Karnataka, India.
Aim:
The study aimed to assess the salivary nitric oxide levels in patients with odontogenic lesions.
Materials And Methods:
The study included 60 individuals: 30 confirmed cases of odontogenic lesions (study group) and 30 healthy controls. Using the Griess reaction method, saliva samples were collected from each participant, and the concentration of nitric oxide was determined as total nitrates and nitrites.
Results:
The data indicate that salivary nitric oxide levels were significantly lower in the study group compared to the control group. Reduced nitric oxide levels in those with odontogenic lesions may indicate a deterioration in the body's defenses against infection.
Conclusion:
Elevated nitric oxide levels in healthy individuals support the role of nitric oxide in oral health by modulating the immune response and inhibiting bacterial growth.
How To Cite This Article:
Cherukunnummal S, Gopinath TPS, Naresh S, et al. Evaluation of Salivary Nitric Oxide Levels in Odontogenic Lesions. Int J Clin Pediatr Dent 2026;19(5):560-562.
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