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Updated: Jun 16, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Comparative efficacy of single exercise interventions on pulmonary function and quality of life in patients with
Xiang Lin1, Xueqi Fan1, Yanling Huang2
1The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Objective:
To systematically compare the effects of various single exercise interventions, including walking, cycling, respiratory muscle training, Taichi, land-based Liuzijue, water-based Liuzijue, Wuqinxi, Baduanjin, Yijinjing, and Yoga, on pulmonary function and quality of life in patients with chronic obstructive pulmonary disease (COPD), and to provide evidence for individualized rehabilitation strategies.
Methods:
Randomized controlled trials (RCTs) on single exercise interventions in patients with COPD were systematically searched in PubMed, EMBASE, Web of Science, Cochrane Library, Scopus, and CNKI from database inception to January 12, 2026. The risk of bias of the included studies was assessed using the Cochrane Risk of Bias Tool in RevMan 5.4, and the quality of evidence was further evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. The network meta-analysis was performed using the "network" command in STATA 17.0.
Results:
A total of 77 RCTs involving 5,831 participants were included. The network meta-analysis showed that water-based Liuzijue was the most effective intervention for improving forced expiratory volume in 1 s as a percentage of the predicted value (FEV1%pred) (MD = 9.51, 95% CI: 3.23 to 15.78; SUCRA = 88.4%), whereas Yijinjing was the most effective intervention for reducing COPD Assessment Test (CAT) scores (MD = -8.37, 95% CI: -12.83 to -3.91; SUCRA = 95.9%).
Conclusion:
Among single exercise interventions for patients with COPD, water-based Liuzijue showed the greatest benefit in improving pulmonary function, while Yijinjing demonstrated the most pronounced effect on quality of life. However, given the limited number of studies on water-based Liuzijue and Yijinjing, these results should be interpreted with caution, and further high-quality randomized controlled trials are needed to validate these findings.
Systematic Review Registration:
https://www.crd.york.ac.uk/PROSPERO/view/CRD420261280662, CRD420261280662.
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