Mortality Outcome Post-MI after PCI and CABG Interventions.

Area of Science:

• Cardiology
• Interventional Cardiology
• Cardiac Surgery

Background:

• Myocardial infarction (MI) remains a leading global cause of death.
• Effective revascularization strategies are crucial for post-MI patient outcomes.

Purpose of the Study:

• To compare three-year mortality outcomes between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in post-MI patients.
• To identify causes of death in patients undergoing PCI versus CABG.

Main Methods:

• Retrospective cohort study of 6,786 post-MI patients (3,542 PCI, 3,244 CABG) from 2020-2024.
• Kaplan-Meier analysis for unadjusted survival and Cox regression for adjusted three-year all-cause mortality.
• Adjustment for baseline demographic and clinical covariates to mitigate confounding.

Main Results:

• Crude mortality was 7.99% for PCI and 11.19% for CABG.
• Adjusted three-year all-cause mortality hazard was not significantly different between PCI and CABG (aHR = 1.12, p = 0.280).
• Independent predictors of mortality included age, diabetes mellitus, and renal complications; non-cardiovascular causes predominated deaths (50-56%).

Conclusions:

• Adjusted three-year mortality is similar between PCI and CABG post-MI.
• Non-cardiac causes represent the majority of deaths, highlighting broader health factors.
• PCI and CABG remain vital, with patient selection guided by heart-team assessment.