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Updated: Jun 16, 2026

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
Published on: May 18, 2018
Colonic Ischemia in a Patient With Pemphigus Vulgaris: Coincidence or Causation
Raveena Joshi1, Deki Tsering2, Emily Krueger2
1Orthopaedics, Virginia Commonwealth University School of Medicine, Richmond, USA.
Abstract:
Pemphigus vulgaris (PV) is a rare autoimmune blistering disorder requiring immunosuppression therapy for optimal treatment. We report the case of a 68-year-old man with newly diagnosed PV who developed colonic ischemia while undergoing treatment with corticosteroids and intravenous immunoglobulin (IVIG). The "acute abdomen" that developed from this ischemia mandated abdominal exploration, resulting in ileocecectomy for effective management. To our knowledge, this is the first documented case of colonic ischemia temporally associated with IVIG therapy in a patient with pemphigus vulgaris. This case highlights the clinical relevance of recognizing the potential for gastrointestinal complications and emphasizing the importance of vigilance while treating PV patients with IVIG.
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