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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

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Related Experiment Video

Updated: Jun 16, 2026

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma
09:17

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Published on: September 13, 2022

Cohort Profile: The Central Denmark Cancer Cohort.

Emese Katalin Vágó1, Henrik Toft Sørensen1, Lars Pedersen1

  • 1Department of Clinical Epidemiology, Center for Population Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.

Clinical Epidemiology
|June 15, 2026
PubMed
Summary
This summary is machine-generated.

The Central Denmark Cancer Cohort (CDCC) links registry data with electronic medical records to enhance cancer research. This comprehensive dataset improves understanding of cancer complications and clinical outcomes for improved patient care.

Keywords:
biomarkerscancer registryelectronic health recordlifestyle factorslongitudinal studyreal-world data

Related Experiment Videos

Last Updated: Jun 16, 2026

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma
09:17

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Published on: September 13, 2022

Area of Science:

  • Oncology
  • Epidemiology
  • Health Informatics

Background:

  • Cancer outcome studies often rely on registry data, which typically lack detailed clinical information.
  • Limitations in existing registries hinder comprehensive research into cancer comorbidities, lifestyle factors, and treatments.
  • There is a need for integrated datasets to facilitate a deeper understanding of cancer's clinical course.

Purpose of the Study:

  • To establish the Central Denmark Cancer Cohort (CDCC) by linking registry data with electronic medical records (EMR).
  • To address limitations in traditional cancer registries by incorporating detailed clinical information.
  • To facilitate research on the clinical course and complications of cancer.

Main Methods:

  • Inclusion of all incident cancer patients (excluding non-melanoma skin cancer) in the Central Denmark Region (2012-2021).
  • Linking Danish Cancer Registry data with the Central Denmark Region Clinical Information System (CDRCIS) and national registries.
  • Extraction and assessment of data on demographics, lifestyle, comorbidities, treatments, and survival outcomes.

Main Results:

  • The CDCC comprises 68,028 patients, with common cancers including prostate, breast, and non-small cell lung carcinoma.
  • High availability of laboratory test results (98.0%) and in-hospital medication data (87.5%) at diagnosis.
  • Median follow-up of 2.6 years revealed a 37.8% mortality rate and a five-year survival of 59.0%.

Conclusions:

  • The CDCC successfully integrates clinical, lifestyle, and laboratory data with cancer registry information.
  • This platform captures crucial factors often missing in registry-based research.
  • The CDCC provides a robust foundation for longitudinal studies on cancer's clinical trajectory.