Related Experiment Video
Updated: Jun 16, 2026

The Use of High-resolution Infrared Thermography (HRIT) for the Study of Ice Nucleation and Ice Propagation in Plants
Published on: May 8, 2015
Molecular mechanisms of plant freezing tolerance: from cold signal perception to adaptive responses
Mingjie Wei1, Xinyuan Liu2, Yawen Wang3
1College of Life Sciences, Shihezi University, Shihezi, China.
Abstract:
Freezing stress poses a threat to plant survival and crop production; therefore, understanding the molecular basis of freezing tolerance and broader cold hardiness is essential for developing cold-hardy crop varieties. This review summarizes molecular responses to freezing, proposes a causal framework from perception to signaling, phenotypes, and applications, and compiles genetic evidence for early signals (Ca2+, ROS, kinases). We outline the ICE-CBF-COR transcriptional network and its multi-layered regulation, and integrate protective metabolic modules (osmotic adjustment, antioxidant defense, membrane lipid remodeling, protective proteins). Phytohormones and epigenetic and non-coding RNA regulation are also discussed, with an emphasis on cold-stress memory. Finally, we discuss strategies to improve freezing tolerance and cold hardiness through natural variation, genome editing, and cold-inducible expression systems, thereby informing molecular breeding and rigorous phenotyping.
Related Concept Videos
Responses to Heat and Cold Stress
Introduction to Plant Diversity
Cell Signaling in Plants
Responses to Drought and Flooding
Responses to Salt Stress
Defenses Against Pathogens and Herbivores
