Intelligent multimodal-energy-driven piezoelectric antibacterial platforms: From structural control to system-level...

Area of Science:

• Biomaterials Science
• Nanotechnology
• Infectious Diseases

Background:

• Antibiotic resistance necessitates novel antibacterial strategies.
• Piezocatalysis presents a physical-chemical alternative to antibiotics.
• Current piezocatalytic systems face limitations in energy sources and design.

Purpose of the Study:

• To review intelligent piezoelectric antibacterial platforms powered by multimodal energy and AI.
• To analyze the evolution from single-energy to multimodal piezoelectric systems.
• To explore synergistic mechanisms and applications in combating bacterial infections.

Main Methods:

• Systematic review of recent research on piezoelectric antibacterial platforms.
• Analysis of piezocatalytic mechanisms and synergistic effects.
• Evaluation of material properties and structural parameter influences.

Main Results:

• Multimodal energy sources and AI enhance piezoelectric antibacterial efficacy.
• Synergistic integration with other components improves antibacterial activity and control.
• Successful applications demonstrated in wound management, implant coatings, and localized infections.

Conclusions:

• Intelligent piezoelectric platforms offer a promising non-antibiotic approach to infection control.
• Further research is needed to address material stability, biosafety, and scalability.
• AI-driven advancements are crucial for future adaptive piezoelectric antibacterial systems.