Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Observational Studies01:11

Observational Studies

Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...
Pharmacokinetic Models: Comparison and Selection Criterion01:26

Pharmacokinetic Models: Comparison and Selection Criterion

Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of injectable HAE on-demand treatments on health-related quality of life: a patient and caregiver interview study.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology·2025
Same author

Estimating Health State Utilities for IDH-Mutant Diffuse Glioma.

PharmacoEconomics - open·2025
Same author

Local adaptation of life-history traits in a seasonal environment.

Journal of evolutionary biology·2025
Same author

Exploring what matters most to patients in relapsed refractory multiple myeloma treatment: a Canadian discrete choice experiment with patients, caregivers and physicians.

BMC cancer·2025
Same author

Exploring public preferences and demand for ovarian cancer screening: a discrete choice experiment.

Frontiers in oncology·2025
Same author

Estimating health state utilities for aromatic L-amino acid decarboxylase deficiency (AADCd) in the United States.

Health and quality of life outcomes·2025

Related Experiment Videos

Patterns in Attribute Selection and Development Reporting in Patient Preference Studies Between 2007-2024: A

Siu Hing Lo1, Rebekah Hall1, Joy Wong2

  • 1Acaster Lloyd, London, UK.

Journal of Health Economics and Outcomes Research
|June 15, 2026
PubMed
Summary
This summary is machine-generated.

Discrete choice experiments (DCEs) require robust attribute selection for validity. This review found inconsistent reporting of formative methods and limited patient partnership, highlighting a need for improved standards in patient preference research.

Keywords:
attribute developmentattribute selectiondiscrete choice experimentspatient and public involvementpatient preferencesresearch reportingreview

Related Experiment Videos

Area of Science:

  • Health Services Research
  • Patient-Reported Outcomes
  • Health Economics

Background:

  • Discrete choice experiments (DCEs) are vital for understanding patient preferences in healthcare.
  • The validity of DCEs hinges on rigorous attribute selection and development.
  • This review addresses reporting patterns and gaps in patient preference studies.

Purpose of the Study:

  • To identify reporting patterns and gaps in the formative attribute selection and development process for patient preference DCEs.
  • To inform future reporting standards for patient preference studies.

Main Methods:

  • A systematic literature search was conducted using Ovid (MEDLINE, EMBASE) for studies on patients, DCEs, and attribute selection.
  • Two reviewers screened studies for eligibility, focusing on formative attribute development methods and reporting quality.
  • Data were synthesized narratively, adhering to PRISMA guidelines.

Main Results:

  • Twenty-eight studies were reviewed, identifying six categories of formative methods.
  • While most studies reported objectives, methodological transparency decreased for details on rationale, sampling, data collection, and analysis.
  • Fewer than half of studies reported how formative findings informed attribute selection, level selection, or wording decisions.
  • Patient engagement as research partners was reported in only 7% of studies.

Conclusions:

  • Inconsistent reporting of formative methods for attribute selection and development was observed.
  • Low reporting levels exist for how formative research informed key attribute decisions.
  • Increased patient engagement as research partners and improved reporting standards are crucial for enhancing the validity and relevance of patient preference research.