Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
Dosage Regimen Designs: Nomograms and Tabulations01:23

Dosage Regimen Designs: Nomograms and Tabulations

Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of a Retrieval-Augmented Generation-Based Large Language Model for Evidence-Based Herb and Supplement Information in Cancer Care.

JMIR cancer·2026
Same author

Nonpharmacologic Approaches for Pain Management in Patients With Cancer Treated With Radiation Therapy.

Seminars in radiation oncology·2026
Same author

Peripheral immunosenescence biomarkers and longitudinal cognitive decline: a large population-based study.

npj aging·2026
Same author

Evaluation of the Association Between Carrageenan and Systemic Inflammation: Results From the National Health and Nutrition Examination Survey.

Molecular nutrition & food research·2026
Same author

Integrative medicine for pain among adolescent and young adult patients with cancer: a scoping review.

Journal of cancer survivorship : research and practice·2026
Same author

Status of Integrative Oncology in Low- and Middle-Income Countries of East and Southeast Asia.

Current oncology reports·2026

Related Experiment Video

Updated: Jun 16, 2026

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

Emerging Patterns in Dietary Supplement Use Among US Adults, 1999-2023.

Chun Sing Lam1, Kelli O'Connell2, Maria J Monroy-Iglesias2

  • 1Integrative Medicine and Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

JAMA Network Open
|June 15, 2026
PubMed
Summary
This summary is machine-generated.

Dietary supplement use among US adults rose significantly from 1999 to 2023, with a notable increase in older adults and a shift towards immune-boosting products. This trend highlights evolving public health considerations.

Related Experiment Videos

Last Updated: Jun 16, 2026

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

Area of Science:

  • Nutrition Science
  • Public Health
  • Epidemiology

Background:

  • Dietary supplement use is prevalent in the US, but long-term data on emerging products and COVID-19 impacts are scarce.
  • Understanding population-level shifts in supplement consumption is crucial for public health research and policy.

Purpose of the Study:

  • To analyze 25-year trends in dietary supplement consumption among US adults.
  • To identify changes in supplement use patterns, including specific product categories and demographic variations.

Main Methods:

  • Cross-sectional analysis of 11 National Health and Nutrition Examination Survey (NHANES) cycles (1999-2023).
  • Inclusion of civilian, noninstitutionalized US adults (≥20 years) reporting supplement use.
  • Survey-weighted binomial regression models to assess trends across demographic subgroups and pandemic periods.

Main Results:

  • Overall supplement use increased from 51% (1999-2000) to 60% (2021-2023).
  • Multivitamin-multimineral (MVMM) use declined, while individual vitamins, minerals, and nonvitamin nonmineral (NVNM) supplements increased.
  • Significant increases observed in older adults (65+ years) and for products marketed for immune health (e.g., zinc, elderberry) during the pandemic.

Conclusions:

  • Dietary supplement use among US adults has trended upward, with diversification beyond MVMMs.
  • A notable increase in supplement use was observed in older adults.
  • Continued monitoring is essential to understand the public health implications of evolving supplement use patterns.