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  1. Home
  3. Epro-guided Symptom Management In Breast Cancer Adjuvant Radiotherapy: A Prospective Controlled Study.
  1. Home
  3. Epro-guided Symptom Management In Breast Cancer Adjuvant Radiotherapy: A Prospective Controlled Study.

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ePRO-Guided Symptom Management In Breast Cancer Adjuvant Radiotherapy: A Prospective Controlled Study.

Shuo Qiao1, Wenjing Yu1, Hong Kou1

  • 1Nursing Department, Shandong Second Medical University.

Journal of Visualized Experiments : Jove
|June 15, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Electronic patient-reported outcomes (ePROs) effectively manage breast cancer radiotherapy symptoms, improving quality of life. This ePRO-guided approach reduced symptom severity and accelerated recovery compared to usual care.

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Area of Science:

  • Oncology
  • Radiotherapy
  • Patient-Reported Outcomes

Background:

  • Breast cancer radiotherapy often causes acute symptoms impacting patient quality of life (QoL).
  • Effective symptom management is crucial for maintaining QoL during treatment.

Purpose of the Study:

  • To evaluate the efficacy of an electronic patient-reported outcome (ePRO)-guided symptom management pathway.
  • To assess the impact of ePRO-guided care on symptom burden and QoL in breast cancer patients undergoing radiotherapy.

Main Methods:

  • Prospective controlled study with 105 breast cancer patients (52 usual care, 53 ePRO-guided).
  • Longitudinal assessment of symptom burden and QoL using validated instruments.
  • Analysis using linear mixed-effects models.

Main Results:

  • The ePRO-guided group showed significantly lower peak symptom severity.
  • Faster symptom recovery and improved QoL trends were observed in the ePRO-guided group.
  • P < 0.05 for all key findings.

Conclusions:

  • Integrating ePRO-guided symptom management into radiotherapy practice reduces acute symptom burden.
  • This approach supports patient-centered care and enhances QoL during breast cancer treatment.