Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chirality in Nature02:30

Chirality in Nature

Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid. The...
Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Chirality02:25

Chirality

Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries
Prochirality02:05

Prochirality

The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Second-Harmonic Hyper-Mie Optical Activity Enables Closed-Loop Chiral Photochemistry.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Second-harmonic chiroptical scattering spectroscopy from plasmonic nanohelices.

Optics express·2026
Same author

Chiral Transformation of a Nanostructured Silver Film by Illumination with Circularly Polarized Light.

ACS nano·2026
Same author

Clinical application of enhanced recovery after surgery in bipolar transurethral vaporization of prostate for benign prostatic hyperplasia.

Frontiers in surgery·2025
Same author

A cross-sectional and bioinformatics-based analysis: perirenal fat thickness as a superior predictor of kidney stone disease.

Lipids in health and disease·2025
Same author

A deep learning-radiomics model for predicting flexible ureteroscope failure: Toward clinical decision support in endourology.

Current problems in surgery·2025

Related Experiment Video

Updated: Jun 17, 2026

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
10:28

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy

Published on: May 27, 2018

Tracking Chirality Evolution in Tellurium Nanocrystals Via Polarization-Resolved Second-Harmonic Scattering.

Ruidong Ji1, Bar Reuven2, Bradleigh Kerrigan1

  • 1Department of Physics, University of Bath, Bath, BA2 7AY, U.K.

Nano Letters
|June 15, 2026
PubMed
Summary

Chirality is key in biology and nanomaterials. Polarization-resolved second-harmonic scattering effectively detects weak chirality in tellurium nanocrystals, outperforming linear circular dichroism.

Keywords:
Chiralitychirality transferchiroptical effectsnanoparticlesnonlinear optics

More Related Videos

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope
09:06

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope

Published on: March 24, 2019

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
05:54

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Published on: September 8, 2023

Related Experiment Videos

Last Updated: Jun 17, 2026

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
10:28

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy

Published on: May 27, 2018

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope
09:06

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope

Published on: March 24, 2019

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
05:54

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Published on: September 8, 2023

Area of Science:

  • Nanomaterials Science
  • Physical Chemistry
  • Solid State Physics

Background:

  • Chirality is fundamental in biological systems and advanced nanomaterials.
  • Detecting weak or residual chirality in liquid-phase nanocrystal synthesis is challenging.
  • Noninvasive probes are needed for tracking chirality evolution in nanocrystals.

Purpose of the Study:

  • To investigate chirality evolution in colloidal tellurium nanocrystals.
  • To compare the sensitivity of linear circular dichroism and second-harmonic scattering for detecting chirality.
  • To establish second-harmonic scattering as a probe for weak structural asymmetry.

Main Methods:

  • Tracking chirality in tellurium nanocrystals with varying degrees of shape chirality.
  • Measuring linear circular dichroism.
  • Utilizing polarization-resolved second-harmonic scattering in forward and right-angled geometries.
  • Analyzing six independent observables: nonlinear g-factor (gNL) and dual-circular polarization metrics (DCP1 and DCP2).

Main Results:

  • Linear circular dichroism decreased significantly with reduced morphological chirality.
  • Polarization-resolved second-harmonic scattering showed clear, handedness-dependent responses.
  • Second-harmonic scattering signals reversed sign between enantiomorphs and remained well-resolved.
  • Geometry dependence of responses indicated interference between mirror symmetry-even and odd nonlinear tensor contributions.

Conclusions:

  • Chiroptical second-harmonic scattering is a highly sensitive probe for weak structural asymmetry.
  • This method is effective for nanocrystals with coupled shape and crystal chirality.
  • Second-harmonic scattering offers a robust alternative to linear circular dichroism for chirality detection.