Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

Transtail Artery Hepatic Artery Catheterization In Rats Under Direct Vision: A Radiation-Free Method For Establishing

Yangkai Fu¹, Lijuan Yao², Simeng Lei¹

¹Division of Hepatobiliary Surgery, Department of General Surgery, Beijing Organ Transplant Center, Beijing Chao-Yang Hospital, Capital Medical University.

Journal of Visualized Experiments : Jove

|June 15, 2026

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reamed and unreamed intramedullary nailing for the treatment of open and closed tibial fractures: a subgroup analysis of randomised trials.

International orthopaedics·2009

Same author

Selective COX-2 inhibitor versus nonselective COX-1 and COX-2 inhibitor in the prevention of heterotopic ossification after total hip arthroplasty: a meta-analysis of randomised trials.

International orthopaedics·2009

Same author

[Study on evaluating sex determining region of the Y as an engrafting track of BMSCs transplantation for repairing osteonecrosis of the femoral head of rabbit].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2009

Same author

Positive association between benign familial infantile convulsions and LGI4.

Brain & development·2009

Same author

Catalytic enantioselective synthesis of chiral phthalides by efficient reductive cyclization of 2-acylarylcarboxylates under aqueous transfer hydrogenation conditions.

Organic letters·2009

Same author

Significance of urinary liver-fatty acid-binding protein in cardiac catheterization in patients with coronary artery disease.

Internal medicine (Tokyo, Japan)·2009

This summary is machine-generated.

This study introduces a radiation-free method for rat liver tumor models using open-laparotomy-guided transtail artery catheterization. This accessible technique enhances preclinical research for trans-arterial chemoembolization (TACE) and drug delivery.

Area of Science:

Preclinical research
Interventional oncology
Animal models

Background:

Rat liver tumor models are crucial for trans-arterial chemoembolization (TACE), drug delivery, and tumor biology research.
Conventional fluoroscopy-guided methods involve high costs, complexity, and radiation exposure.
There is a need for accessible, radiation-free techniques in preclinical settings.

Purpose of the Study:

To present a novel, radiation-free protocol for catheterization in rat liver tumor models.
To detail a step-by-step procedure for open-laparotomy-guided transtail artery catheterization.
To offer an accessible alternative to fluoroscopy-guided interventions.

Main Methods:

The protocol involves standardized anesthesia and exposure of the ventral caudal artery (VCA).

More Related Videos

Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model

Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model

Published on: January 30, 2015

Related Experiment Videos

Last Updated: Jun 17, 2026

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model

Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model

Published on: January 30, 2015

A midline laparotomy allows direct visualization of the hepatoduodenal anatomy.

A 1.6 Fr microcatheter is advanced into the common hepatic artery (CHA) or proper hepatic artery (PHA) using a microguidewire.

Main Results:

The study validated the technique in 32 rats.
A high technical success rate of 96.9% (31/32) was achieved.
The mean procedure time was 22.5 ± 2.3 minutes.

Conclusions:

This radiation-free transtail artery catheterization is an accessible and reproducible method.
It provides a transparent platform for localized therapeutic evaluation and embolic biology studies.
The technique lowers the barrier for establishing high-quality interventional models in preclinical research.