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Diode Laser-Assisted Oral Frenectomy as a Modern Alternative: A Systematic Review and Meta-Analysis.

Zahra Baghani¹, Pouria Soltaninezhad², Hossein Assarzadeh³

¹Department of Periodontics, Faculty of Dentistry, Sabzevar University of Medical Sciences, Sabzevar, Iran.

Lasers in Surgery and Medicine

|June 15, 2026

Summary

Diode laser frenectomy significantly reduces postoperative pain and intraoperative bleeding compared to the scalpel technique. While wound healing showed no significant difference at seven days, laser use offers a less painful alternative for oral frenectomies.

Keywords:

epithelialization hemostasis low‐level laser therapy postoperative complications wound healing

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Area of Science:

Oral surgery
Laser dentistry
Minimally invasive procedures

Background:

Diode laser-assisted oral frenectomy is a minimally invasive technique for anatomical restrictions.
Evidence on its impact on wound healing and postoperative complications is limited.
This study compares diode laser frenectomy with the conventional scalpel technique.

Purpose of the Study:

To evaluate the clinical efficacy of diode laser-assisted frenectomy.
To compare diode laser frenectomy with the scalpel technique regarding postoperative discomfort, intraoperative hemorrhage, and wound healing.

Main Methods:

Systematic review and meta-analysis adhering to PRISMA guidelines.
Searched for comparative studies of diode laser vs. scalpel frenectomy (Jan 2015-Dec 2025).
Analyzed pooled outcomes (pain, hemorrhage, healing) using a random-effects model and assessed publication bias.

Main Results:

Fourteen studies were included in the meta-analysis.
Diode laser significantly reduced postoperative pain on day 1 and day 7.
Diode laser also significantly reduced intraoperative hemorrhage; wound healing at day 7 showed no significant difference.

Conclusions:

Diode laser-assisted frenectomy is effective in reducing postoperative pain and intraoperative hemorrhage.
No significant difference in wound healing was observed at seven days.
Future research should standardize wound healing metrics and include cost-effectiveness.