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Related Concept Videos

Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
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Articles linked to this work by shared authors, journal, and citation graph.

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Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.

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Simplified Tools, Complex Decisions: These Are Rhythm Procedures: Why AF Ablation, Leadless Pacing, and Left Atrial Appendage Occlusion Require Rhythm-Centered Care.

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Related Experiment Video

Updated: Jun 17, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

External Suture-Retention Device Versus Manual Compression for Venous Access-Site Closure Post-Ablation: The LockeT

Aashish Katapadi1, Karnik Patel2, Nikhila Chelikam1

  • 1Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.

Journal of Cardiovascular Electrophysiology
|June 15, 2026
PubMed
Summary

The LockeT device offers effective hemostasis and fewer groin complications after atrial fibrillation ablation compared to manual compression. It significantly reduces time to ambulation and time to discharge, improving patient recovery.

Keywords:
access‐sitecatheter ablationclosuremanual compressionsuture‐retention‐devicevenous

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A Training and Testing System for Performing Vascular Reconstruction In Vitro
09:52

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Published on: October 26, 2019

Related Experiment Videos

Last Updated: Jun 17, 2026

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08:05

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Published on: December 9, 2022

A Training and Testing System for Performing Vascular Reconstruction In Vitro
09:52

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Published on: October 26, 2019

Area of Science:

  • Cardiovascular Interventions
  • Medical Device Technology
  • Patient Outcomes Research

Background:

  • Manual compression (MC) for vascular access closure has limitations including prolonged immobilization and higher resource utilization.
  • The LockeT external suture retention device aims to overcome these shortcomings.
  • Evaluating novel closure devices is crucial for improving procedural efficiency and patient recovery.

Purpose of the Study:

  • To compare the safety and effectiveness of the LockeT device against manual compression (MC) for vascular closure.
  • To assess key outcomes including hemostasis, time to ambulation, time to discharge, and complication rates.
  • To evaluate patient comfort and perform a cost analysis comparing the two closure methods.

Main Methods:

  • A prospective, single-center study randomized patients undergoing atrial fibrillation ablation to either MC or LockeT closure (1:1 ratio).
  • Vascular access sites were analyzed for hemostasis at two hours (HA2H), time to ambulation (TTA), time to discharge (TTD), and same-day discharge (SDD) rates.
  • Groin complications, patient comfort, and procedural costs were systematically assessed for both groups.

Main Results:

  • No significant differences were observed in procedural times or maximum sheath size between LockeT and MC groups.
  • LockeT demonstrated a significantly shorter time to ambulation (TTA) and time to discharge (TTD) compared to MC.
  • The LockeT group experienced significantly fewer cumulative groin complications (2.9% vs. 11.2%) compared to the MC group.

Conclusions:

  • The LockeT device provides effective hemostasis and is associated with significantly reduced time to ambulation and discharge.
  • LockeT offers a safe alternative to manual compression, with a notable reduction in groin complications.
  • Further investigation into the long-term efficacy and broader application of the LockeT device is warranted.