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Oropouche virus: viral evolution, epidemiological trends, and challenges for control
Ralph Huits1, Maria D Mileno2, Francesca F Norman3
1Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy.
Current Opinion in Infectious Diseases
|June 15, 2026
Summary
Oropouche virus (OROV) is an emerging arbovirus posing a public health threat. This review synthesizes current knowledge on OROV epidemiology, virology, and clinical aspects to guide control strategies.
Area of Science:
- Arbovirology
- Public Health
- Infectious Diseases
Background:
- Oropouche virus (OROV) has emerged as a significant public health concern.
- OROV's threat extends beyond its traditional Amazonian region.
Purpose of the Study:
- To review current epidemiological, virological, clinical, and ecological knowledge of OROV.
- To inform health practitioners, public health authorities, and researchers.
- To facilitate the development of OROV control strategies.
Main Methods:
- Comprehensive literature review of OROV.
- Synthesis of epidemiological data.
- Analysis of virological and ecological factors.
Main Results:
- Description of OROV's epidemiological, virological, ecological, and clinical characteristics.
- Focus on lessons learned from OROV's recent expansion.
- Identification of needs for OROV control and management.
Conclusions:
- OROV has recently reemerged and expanded beyond the Amazon Basin.
- Discussion of OROV ecology, epidemiology, virology, and clinical presentations.
- Identification of knowledge gaps in OROV research and control.
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