Related Experiment Video
Updated: Jun 17, 2026
08:06
Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
The Effect of 4:3 Intermittent Fasting on Weight Loss at 12 Months
Danielle M Ostendorf1, Matthew J Breit2, Zhaoxing Pan3
1Anschutz Health and Wellness Center, University of Colorado, School of Medicine, Anschutz Medical Campus, Aurora, Colorado; Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado; and Department of Kinesiology, Recreation and Sports Studies, University of Tennessee Knoxville, Knoxville, Tennessee.
Annals of Internal Medicine
|June 15, 2026
Summary
No abstract available in PubMed .
Related Concept Videos
01:24Metabolic States of the Body: Fasting and Starvation
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
01:18Metabolic States of the Body: The Postabsorptive State
The postabsorptive state usually starts about four hours after a meal and lasts until the next meal is eaten. During this time, the digestive system stops absorbing nutrients, and the body uses stored energy reserves to maintain stable blood glucose levels.
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...