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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Jun 17, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Melanoma: Cutaneous, Version 2.2026, NCCN Clinical Practice Guidelines In Oncology.

Susan M Swetter1, Douglas Johnson2, Mark R Albertini3

  • 11Stanford Cancer Institute.

Journal of the National Comprehensive Cancer Network : JNCCN
|June 15, 2026
PubMed
Summary
This summary is machine-generated.

This summary covers NCCN Guidelines for Cutaneous Melanoma, focusing on risk factors for melanoma development. Early assessment of phenotypic, personal, genetic, and environmental factors is crucial for patient outcomes.

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Last Updated: Jun 17, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
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A Melanoma Patient-Derived Xenograft Model
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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
06:09

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Area of Science:

  • Oncology
  • Dermatology

Background:

  • Cutaneous melanoma is a prevalent cancer in the U.S.
  • Patient outcomes are strongly linked to the stage at diagnosis.
  • Localized disease and smaller tumors generally indicate a better prognosis.

Purpose of the Study:

  • To outline strategies for cutaneous melanoma diagnosis, treatment, and follow-up.
  • To highlight key risk factors influencing melanoma development.
  • To guide initial patient assessments for cutaneous melanoma.

Main Methods:

  • Focus on risk factors for cutaneous melanoma development.
  • Consideration of phenotypic predispositions.
  • Evaluation of personal medical history and comorbidities.
  • Assessment of genetic predispositions.
  • Analysis of environmental factors.

Main Results:

  • Identified four key categories of risk factors for cutaneous melanoma.
  • Emphasized the importance of initial assessment for risk stratification.
  • Highlighted the impact of various factors on melanoma prognosis.

Conclusions:

  • Comprehensive risk factor assessment is vital for managing cutaneous melanoma.
  • Understanding predispositions aids in early detection and intervention.
  • Adherence to NCCN Guidelines ensures optimal patient care pathways.