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Related Experiment Video

Updated: Jun 17, 2026

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
07:21

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

Right ventricular strain analysis with positron emission tomography-derived feature tracking: Direct comparison with

Masataka Katahira1, Kenji Fukushima2, Ayano Ikeda1

  • 1Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|June 15, 2026
PubMed
Summary

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Positron emission tomography (PET) can now assess right ventricle (RV) strain, a key indicator of heart function. This new PET feature tracking method shows strong correlation with magnetic resonance imaging (MRI), offering a promising tool for detecting RV dysfunction.

Area of Science:

  • Cardiovascular imaging
  • Nuclear cardiology
  • Cardiac mechanics

Background:

  • Right ventricle (RV) function assessment is challenging with standard Positron Emission Tomography (PET).
  • Myocardial strain analysis is a sensitive method for detecting subtle cardiac wall dysfunction.
  • Novel PET feature tracking techniques are being developed for comprehensive cardiac evaluation.

Purpose of the Study:

  • To evaluate the feasibility of quantifying RV strain using a new PET feature tracking technique.
  • To compare RV strain measurements derived from PET with those from cardiac magnetic resonance (CMR) imaging.
  • To establish PET as a potential tool for assessing RV myocardial function.

Main Methods:

  • Retrospective analysis of 123 patients undergoing rest 13N ammonia PET-MR.
Keywords:
Feature trackingIschemic heart diseaseMyocardial strainPET/MR

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MRI and PET in Mouse Models of Myocardial Infarction

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Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
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Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

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Related Experiment Videos

Last Updated: Jun 17, 2026

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
07:21

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

MRI and PET in Mouse Models of Myocardial Infarction
10:46

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
11:13

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Published on: May 24, 2021

  • Semi-automatic PET feature tracking software used to derive RV global longitudinal strain (GLS) and circumferential strain (GCS).
  • Simultaneous breath-hold cine MR imaging served as the reference standard for strain quantification.

    • Main Results:

    • PET-derived RV GLS and GCS showed strong correlations with CMR measurements (r=0.77 for GLS, r=0.74 for GCS; p<0.0001).
    • Bland-Altman analysis indicated acceptable agreement between PET and CMR strain values.
    • Significant proportional bias was observed, but limits of agreement were considered acceptable for clinical utility.

    Conclusions:

    • PET-derived RV strain analysis using feature tracking correlates significantly with CMR strain.
    • This novel PET technique shows potential for detecting RV wall dysfunction in clinical practice.
    • PET feature tracking may enhance the assessment of RV function in routine cardiovascular imaging.