Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Modeling in Therapy01:26

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mice prenatally exposed to valproic acid do not show autism-related disorders when fed with polyunsaturated fatty acid-enriched diets.

Scientific reports·2023
Same author

Age-related behavioural and striatal dysfunctions in Shank3<sup>ΔC/ΔC</sup> mouse model of autism spectrum disorder.

The European journal of neuroscience·2023
Same author

Genetic and environmental mouse models of autism reproduce the spectrum of the disease.

Journal of neural transmission (Vienna, Austria : 1996)·2022
Same author

Better Outcomes with Intranigral versus Intrastriatal Cell Transplantation: Relevance for Parkinson's Disease.

Cells·2022
Same author

Major motor and gait deficits with sexual dimorphism in a Shank3 mutant mouse model.

Molecular autism·2021
Same author

Sex-dependent behavioral deficits and neuropathology in a maternal immune activation model of autism.

Translational psychiatry·2019

Related Experiment Video

Updated: Jun 17, 2026

Strategies for Assessing Autistic-Like Behaviors in Mice
07:38

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Motor Disorders in Autism: From Comorbidity to Core Criterion.

Mohamed Jaber1,2

  • 1Laboratoire de Neurosciences Expérimentales et Cliniques, Université de Poitiers, INSERM, Poitiers, France.

Autism Research : Official Journal of the International Society for Autism Research
|June 15, 2026
PubMed
Summary

Autism Spectrum Disorder (ASD) diagnosis should include motor and gait signs beyond repetitive movements. Integrating these fundamental motor skills can improve early identification and tailored interventions for ASD.

Keywords:
ASDbasal gangliacerebellumdiagnosis criteriaembodied cognitiongaitmotor screeningneurodevelopment

More Related Videos

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
05:32

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

Related Experiment Videos

Last Updated: Jun 17, 2026

Strategies for Assessing Autistic-Like Behaviors in Mice
07:38

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
05:32

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

Area of Science:

  • Neurology
  • Developmental Pediatrics
  • Movement Science

Background:

  • Repetitive movements are key Autism Spectrum Disorder (ASD) diagnostic criteria.
  • Motor disturbances like gait atypicalities and postural control issues are often overlooked.
  • Evidence suggests motor signs in ASD are fundamental, not secondary comorbidities.

Purpose of the Study:

  • Advocate for integrating motor dimensions into ASD diagnostic frameworks.
  • Highlight the potential of early motor signs to predict communication outcomes.
  • Propose a paradigm shift towards a motor-informed model of autism.

Main Methods:

  • Review of experimental and clinical findings on motor dysfunctions in ASD.
  • Analysis of current diagnostic systems (DSM, ICD) and their limitations.
  • Synthesis of evidence linking motor signs to neurological underpinnings (cerebellum, basal ganglia).

Main Results:

  • Motor dysfunctions in ASD are linked to cerebellar/basal ganglia issues, impaired multisensory integration, and disrupted emotion-motor coupling.
  • Early discernible motor and gait signs may predict communication outcomes.
  • Current diagnostic systems may miss fundamental motor aspects of ASD.

Conclusions:

  • Motor and gait signs, beyond repetitive movements, should be incorporated into future ASD diagnostic criteria (DSM, ICD).
  • Integrating motor screening into pediatric surveillance can enhance early ASD identification.
  • An embodied, motor-informed model is crucial for transforming ASD diagnosis and care.