Related Experiment Video
Updated: Jun 17, 2026
04:12
Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
Published on: January 19, 2024
The Effects of Tranexamic Acid Injections on Surgical Scars: A Retrospective Study.
Zhe Cao1,2,3, Jun Liu2,3, Ling Yun Wu2,3
1The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Aesthetic Plastic Surgery
|June 15, 2026
Summary
Immediate application of Tranexamic Acid (TXA) after surgery significantly improves surgical scar appearance and reduces scar width. This early intervention offers a promising method for better surgical scar outcomes.
Area of Science:
- Plastic Surgery
- Dermatology
- Wound Healing
Background:
- Tranexamic Acid (TXA) is known for melasma treatment and hemostasis.
- Limited research exists on TXA's efficacy for improving surgical scars.
- Early intervention is crucial for optimal surgical scar outcomes.
Purpose of the Study:
- To investigate the effectiveness of immediate postoperative Tranexamic Acid (TXA) injections in preventing surgical scar formation.
- To assess TXA's impact on scar appearance and quality when applied directly to the incision site.
Main Methods:
- Prospective split-scar study involving 30 consecutive surgical patients.
- Randomized injection of TXA into half of each surgical wound closure immediately post-surgery.
- Scars evaluated using Visual Analogue Scale (VAS) and modified Stony Brook Scar Evaluation Scale (mSBSES).
Main Results:
- TXA-treated scar sides showed significantly improved VAS and mSBSES scores (p<0.05).
- Visible improvements in scar appearance, including narrower scars, were observed.
- No severe complications or adverse events were reported in the TXA-treated group.
Conclusions:
- Immediate postsurgical application of TXA via injection improves the aesthetic outcome of surgical scars.
- TXA demonstrates potential as an effective early intervention for managing surgical scars.