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Updated: Jun 17, 2026

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Autologous and Implant-Based Breast Reconstruction Demonstrate Equivalent Psychiatric Outcomes at Long-Term
Ron Skorochod1, Nir Zontag2,3, Yoram Wolf1,4
1Unit of Plastic and Reconstructive Surgery, Hillel Yaffe Medical Center, Hadera, Israel.
Aesthetic Plastic Surgery
|June 15, 2026
Summary
Breast reconstruction using autologous tissue or implants shows similar long-term psychiatric risks. Patient-reported satisfaction does not correlate with objective psychiatric outcomes, emphasizing personalized care decisions for breast cancer patients.
Area of Science:
- Oncology
- Plastic Surgery
- Psychiatry
Background:
- Breast reconstruction is crucial for breast cancer patients.
- Autologous reconstruction may offer psychological benefits, but objective data on psychiatric outcomes are scarce.
Purpose of the Study:
- To compare the incidence of new psychiatric disorders after autologous versus implant-based breast reconstruction.
Main Methods:
- Retrospective cohort analysis of over 29,000 patients from the TriNetX network.
- Propensity score matching (PSM) to balance patient demographics and clinical factors.
- Assessed new diagnoses of anxiety, depression, and other psychiatric disorders within 5 years post-surgery.
Main Results:
- 14,805 patients per group after 1:1 PSM.
- No significant difference in new psychiatric diagnoses between autologous and implant-based reconstruction cohorts within 5 years.
- Specific diagnoses including anxiety, depression, and mood disorders showed similar incidence rates.
Conclusions:
- Both breast reconstruction methods present comparable long-term psychiatric risks.
- Patient-reported outcomes do not fully align with objective psychiatric measures.
- Decision-making should prioritize patient-centered discussions on needs and preferences.