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Assessment of Risk Factors for Surgical Site Infection in Diabetic Patients Undergoing Elective Surgery
Muhammad Sameer Anwar1, Rimsha Malik2, Hafiz Muhammad Shoaib3
1Medicine, Hayat Memorial Teaching Hospital, Lahore, PAK.
Insights
Surgical site infections (SSIs) are common in diabetic patients. Poor glycemic control, prolonged surgery, contaminated wounds, and smoking are key risk factors for SSIs in this population.
Area of Science:
- Medical research
- Surgical outcomes
- Diabetic patient care
Background:
- Surgical site infections (SSIs) are a significant postoperative complication.
- Diabetic patients face higher SSI risks due to impaired immunity and delayed wound healing.
Purpose of the Study:
- To identify risk factors for SSIs in diabetic patients undergoing elective surgery.
- To analyze the association between perioperative factors and SSI development.
Main Methods:
- Retrospective study of 150 diabetic patients undergoing elective surgery.
- Data collected on glycemic indicators, comorbidities, operative details, and wound status.
- Non-probability consecutive sampling used at Children Hospital Lahore.
Main Results:
- Overall SSI rate was 25.3%.
- Higher HbA1c, prolonged operative duration (>2 hours), contaminated wound classification, and smoking were significantly associated with SSIs.
- Poor glycemic control, prolonged surgery, contaminated wounds, and smoking were independent predictors of SSI.
Conclusions:
- SSIs in diabetic patients are strongly linked to modifiable perioperative factors.
- Optimizing glycemic control and addressing factors like smoking and operative duration can reduce SSI risk.
- Contaminated wounds and prolonged surgery are critical factors increasing infection risk.
Background:
Surgical site infections (SSIs) remain a major postoperative complication, particularly among diabetic patients who are inherently at higher risk due to impaired immunity and delayed wound healing.
Objective:
To assess the risk factors associated with SSIs in diabetic patients undergoing elective surgical procedures.
Methods:
This retrospective study was conducted at Children Hospital Lahore, from April 2024 to April 2025. A total of 150 diabetic patients scheduled for elective surgery were enrolled using non-probability consecutive sampling. Preoperative, intraoperative, and postoperative variables were recorded, including glycemic indicators, comorbidities, operative duration, wound classification, antibiotic timing, and postoperative wound status.
Results:
The mean age of participants was 57.8 ± 11.4 years, and 58.7% were male. The overall SSI rate was 25.3% (n = 38). Higher HbA1c levels were significantly associated with SSI (8.4 ± 1.3 vs. 7.1 ± 1.0, p < 0.001). Operative duration of two or more hours (p = 0.02), contaminated wound classification (p = 0.01), smoking (p = 0.03), and incorrect antibiotic prophylaxis timing (p = 0.04) were also significantly correlated with infection. Logistic regression identified poor glycemic control (adjusted odds ratio (AOR) 3.1, 95% CI: 1.6-5.9), prolonged surgery (AOR 2.4, 95% CI: 1.1-4.8), contaminated wound class (AOR 2.9, 95% CI: 1.3-6.5), and smoking (AOR 1.9, 95% CI: 1.01-3.8) as independent predictors of SSI. Patients who developed SSI had significantly longer hospital stays (9.8 ± 3.1 vs. 5.3 ± 1.9 days, p < 0.001).
Conclusion:
It is concluded that SSIs in diabetic patients are strongly linked to modifiable perioperative factors. Poor glycemic control, prolonged operative duration, contaminated wounds, and smoking significantly increase infection risk.
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