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Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

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Published on: May 30, 2025

Female Sexual Dysfunction Across Diabetes Types Compared to Non-Diabetic Controls: A Systematic Review and

Özden Tandoğan¹

¹Department of Nursing, Faculty of Health Sciences, Istanbul Arel University, Istanbul, Turkey.

Journal of Sex & Marital Therapy

|June 16, 2026

Summary

This summary is machine-generated.

Women with diabetes mellitus (DM) experience significantly reduced female sexual function compared to non-diabetic individuals. This association was observed across Type 1 and Type 2 DM, with menopausal status influencing the effect size.

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Last Updated: Jun 17, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

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Published on: May 30, 2025

Area of Science:

Endocrinology
Reproductive Health
Medical Statistics

Background:

Diabetes mellitus (DM) is a prevalent condition affecting numerous bodily functions.
Female sexual dysfunction (FSD) is a common concern impacting quality of life.
The relationship between DM and FSD requires further investigation.

Purpose of the Study:

To quantitatively synthesize evidence on female sexual function in women with Type 1 or Type 2 DM compared to non-diabetic controls.
To assess the impact of diabetes type and menopausal status on sexual function.

Main Methods:

A systematic literature search was conducted across PubMed, Scopus, Web of Science, and Cochrane up to March 2026.
Observational studies utilizing the Female Sexual Function Index (FSFI) were included.
A random-effects meta-analysis was performed to calculate the standardized mean difference (SMD) and conduct subgroup analyses.

Main Results:

Diabetic women exhibited significantly lower FSFI scores compared to controls (SMD = -0.764, p < .001).
The effect size was numerically larger for Type 1 DM (SMD = -0.994) than Type 2 DM (SMD = -0.627), though not statistically significant.
Menopausal status moderated the effect, with premenopausal samples showing a larger negative impact (SMD = -0.911) than mixed-status samples (SMD = -0.434).
High heterogeneity (I² = 91.65%) and a prediction interval crossing zero necessitate cautious interpretation.

Conclusions:

Diabetes mellitus is associated with impaired female sexual function.
While Type 1 DM showed a numerically larger effect, both types of diabetes negatively impact sexual function.
Menopausal status plays a role in the severity of FSD in diabetic women.