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Multifunctional Janus hemostatic dressings tailored for complex coagulation processes.
Liyan Ding1, Yicheng Zhang1, Weijie Guo1
1College of Chemistry and Materials Science, Fujian Normal University, Fuzhou 350007, People's Republic of China. chenqh@fjnu.edu.cn.
Biomaterials Science
|June 16, 2026
Summary
Janus materials offer a novel approach to hemostatic dressings by independently performing distinct functions. This innovation aims to improve trauma treatment by enhancing vasoconstriction, platelet aggregation, and blood coagulation.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Materials Chemistry
Background:
- Hemostasis is crucial for trauma treatment, involving vasoconstriction, platelet aggregation, and blood coagulation.
- Current hemostatic dressings often use composite materials, but isotropic designs face functional interference.
- Janus materials, with distinct sides, offer a potential solution for independent functional performance.
Purpose of the Study:
- To review the hemostatic process and mechanisms.
- To explore the application of Janus materials in hemostatic management.
- To discuss future prospects and challenges of Janus hemostatic dressings.
Main Methods:
- Overview of hemostasis mechanisms.
- Review of recent advances in Janus-structured hemostatic materials.
- Analysis of development prospects and challenges.
Main Results:
- Janus materials enable compartmentalized functions for enhanced hemostasis.
- Distinct chemical properties on each side allow independent optimization of hemostatic functions.
- This approach overcomes limitations of traditional isotropic hybrid materials.
Conclusions:
- Janus hemostatic dressings represent a promising advancement in trauma management.
- Further research into Janus materials can lead to more effective hemostatic therapies.
- Addressing challenges will be key to realizing the full potential of Janus hemostatic dressings.
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