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AMS-HD: Hyperdimensional Computing for Real-Time and Energy-Efficient Acute Mountain Sickness Detection
IEEE Transactions on Bio-Medical Engineering
|June 16, 2026
Summary
A new hyperdimensional computing framework, AMS-HD, enables real-time detection of acute mountain sickness (AMS) using wearable sensors. It offers high accuracy with significantly reduced power and memory requirements for continuous health monitoring.
Area of Science:
- Biomedical Engineering
- Computer Science
- Altitude Medicine
Background:
- Acute mountain sickness (AMS) is a common illness at high altitudes, posing risks of severe health complications.
- Current machine learning methods for AMS detection lack the efficiency needed for continuous monitoring on wearable devices.
Purpose of the Study:
- To introduce AMS-HD, the first hyperdimensional computing (HDC) framework for real-time AMS detection.
- To develop a hardware-efficient solution for continuous AMS monitoring using wearable physiological signals.
Main Methods:
- Developed a complete HDC framework integrating feature selection, hypervector encoding, and positional projection.
- Implemented and validated the framework on ARM, FPGA, and smartwatch-smartphone platforms.
- Utilized wearable SpO2 and heart rate signals for AMS severity classification.
Main Results:
- AMS-HD achieved up to 91% accuracy and 90% F1-score in binary classification, outperforming SVM and MLP baselines.
- On FPGA, AMS-HD demonstrated significant reductions in LUT (7.3x) and flip-flop (5.8x) usage, with 3.9x lower power consumption compared to MLP.
- On mobile platforms, AMS-HD required minimal resources: 1% battery per session, 60 Bytes of memory, and 2.50 ms inference time.
Conclusions:
- AMS-HD offers a scalable, hardware-aware alternative for real-time AMS monitoring.
- The framework achieves competitive performance with substantially lower resource consumption than conventional ML methods.
- This work bridges wearable inference and low-level hardware deployment for resource-constrained health monitoring.

