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Published on: February 3, 2016
Gastric myoelectrical activity and autonomic dysfunction in children with IBD and IBS: An electrogastrographic and
Ana Močić Pavić1, Paola Ruška1, Zrinjka Mišak2
1Children's Hospital Zagreb, Department of Pediatrics, Zagreb, Croatia.
Abstract:
Sixty-two children (18 with inflammatory bowel disease [IBD], 28 with irritable bowel syndrome [IBS], 18 healthy controls) underwent pre- and postprandial electrogastrography and autonomic assessment with the Composite Autonomic Symptom Score-31 (COMPASS-31) and Composite Autonomic Severity Scale (CASS). No between-group differences in EGG parameters were observed. Children with IBS showed increased postprandial normogastria. Higher autonomic symptom burden correlated with lower postprandial power dominant frequency, and symptomatic dysautonomia was associated with reduced postprandial power dominant frequency. These exploratory findings suggest a link between autonomic symptoms and postprandial gastric activity and warrant confirmation in larger cohorts.
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