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Related Experiment Video

Updated: Jun 18, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
06:38

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

Skeletal Stabilization After Sagittal Split Osteotomy Using a Biodegradable Osteosynthesis System: A Pilot Study.

Soichiro Negishi1, Hitoshi Sato1, Motohiro Tanaka1

  • 1Department of Oral and Maxillofacial Surgery, Showa Medical University School of Dentistry.

The Journal of Craniofacial Surgery
|June 16, 2026
PubMed
Summary
This summary is machine-generated.

Biodegradable plates showed acceptable short-term stability in sagittal split ramus osteotomy (SSRO) for mandibular prognathism. Titanium plates offered greater skeletal stability than biodegradable plates in this pilot study.

Keywords:
Biodegradable osteosynthesis systembox-type platepilot studysagittal split ramus osteotomy (SSRO)skeletal stability

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Area of Science:

  • Orthognathic Surgery
  • Biodegradable Osteosynthesis
  • Skeletal Stability

Background:

  • Reliability of biodegradable osteosynthesis in orthognathic surgery is understudied.
  • Limited research exists on biodegradable systems post-mandibular osteotomy, specifically sagittal split ramus osteotomy (SSRO).

Purpose of the Study:

  • To compare the safety and skeletal stability of titanium versus biodegradable fixation systems in SSRO for mandibular prognathism.

Main Methods:

  • Pilot study comparing curved titanium plates (Ti group) and box-type biodegradable plates (Bi group) after SSRO.
  • Analysis of lateral cephalograms, frontal cephalograms, and CT scans at baseline, early post-op, and 6 months post-op.

Main Results:

  • No significant skeletal angle changes were observed in the titanium group from early to late post-op.
  • Significant changes in mandibular plane, ramus plane, and gonial angles were noted in the biodegradable group.
  • No significant differences in the positional changes of Point B, menton, or pogonion between groups.

Conclusions:

  • Box-type biodegradable plates may offer acceptable short-term skeletal stability and safety in SSRO.
  • Larger prospective studies are needed to confirm these findings and compare long-term outcomes.