The Peezy Device Compared With Midstream Clean Catch in an Obstetric Population: A Randomized Controlled Trial

Area of Science:

• Obstetrics and Gynecology
• Infectious Diseases
• Urology

Background:

• Screening for asymptomatic bacteriuria in pregnancy is crucial to prevent complications like acute pyelonephritis.
• The standard clean catch midstream urine collection method is prone to contamination, especially in patients with obesity.
• The Peezy device, designed to minimize contamination, has not been previously studied in pregnant populations.

Purpose of the Study:

• To compare urine culture contamination rates between the Peezy device and the standard clean catch method in pregnant women before 20 weeks' gestation.
• To assess if the Peezy device's effectiveness in reducing contamination varies by body mass index (BMI).

Main Methods:

• A randomized controlled trial involving adult English-speaking women undergoing prenatal care.
• Participants were randomized to use either the Peezy device or the standard clean catch method for urine collection.
• Intention-to-treat analysis was used to compare contamination rates, with stratification by BMI status.

Main Results:

• The overall contamination rate was 61.3% for the standard clean catch group and 52.5% for the Peezy group.
• No statistically significant difference in contamination rates was observed between the Peezy and clean catch groups (OR=0.7, 95% CI: 0.4-1.2, p=0.19).
• Stratification by BMI did not reveal any significant difference in contamination rates between the groups.

Conclusions:

• This study did not demonstrate a reduction in urine culture contamination rates using the Peezy device in pregnant women.
• The findings suggest that the Peezy device may not be superior to the standard clean catch method for reducing contamination in this population.
• Further research may be needed to explore alternative methods for improving urine sample quality in pregnant individuals.