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Updated: Jun 18, 2026
Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
Published on: August 30, 2019
Data from a UK-based multicentre randomised feasibility study investigating the management of post-traumatic benign
Rebecca M Smith1, Bithi Sahu2, Caroline Burgess3
1Centre of Vestibular Neurology, Imperial College London, London, UK Rebecca.smith@imperial.ac.uk.
Objectives:
Traumatic brain injury commonly causes dizziness and balance problems. Benign paroxysmal positional vertigo (BPPV) is the most frequent cause of inner-ear related post-traumatic vestibular dysfunction. However, optimal assessment and treatment practices are poorly evidenced. Using a mixed methods approach, we aimed to explore the feasibility of managing post-traumatic BPPV.
Design:
A mixed-methods randomised feasibility study. In this paper, quantitative and qualitative data relating to key feasibility targets around recruitment, randomisation and assessment and treatment were selected and integrated to provide an in-depth understanding of BPPV management.
Setting:
Three UK major trauma centres PARTICIPANTS: Hospitalised adults with post-traumatic BPPV.
Interventions:
Patients were randomised to one of three interventions (repositioning manoeuvres, Brandt-Daroff exercises and advice).
Results:
Screening and recruitment varied between sites due to individual and site-specific factors. Randomisation to advice was experienced differently by healthcare professionals and patients, suggesting that changes to the study design of a future effectiveness trial may be required. Assessment and treatment were acceptable to participants, supporting advancement to an effectiveness trial.
Conclusions:
Integration of qualitative and quantitative data revealed new findings relating to the primary outcomes of the feasibility study, while strengths and weaknesses of the trial design were also elucidated. Taken together, such data will influence and enhance the design of a future trial.
Trial Registration Number:
ISRCTN91943864.
