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Updated: Jun 18, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Moving the goalposts from symptom control to preventing airway remodeling in preschool asthma

Larry C Lands1

  • 1Department of Paediatrics, Pediatric Respiratory Medicine, McGill University Health Centre (MUHC), 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada.

Paediatric Respiratory Reviews
|June 16, 2026
PubMed

Insights

Recurrent wheezing in young children is common. Further research is needed on preschool asthma definitions, phenotypes, investigations, and advanced therapeutics like biologics.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology

Background:

  • Recurrent wheezing is a frequent pediatric respiratory issue.
  • Current understanding of preschool asthma requires further development.

Purpose of the Study:

  • To address the need for clarity in preschool asthma.
  • To explore phenotypes, diagnostic methods, and therapeutic strategies.

Main Methods:

  • Case illustration approach.
  • Review of current literature on preschool wheezing and asthma.

Main Results:

  • Highlights the complexity of diagnosing and managing preschool asthma.
  • Identifies gaps in knowledge regarding phenotypes and treatment.

Conclusions:

  • Emphasizes the need for standardized definitions and approaches for preschool asthma.
  • Suggests further research into targeted therapies, including biologics.

Keywords:
AtopyBiologicsBiomarkersCytokinesRhinovirus

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