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Remission in Global Airway Diseases: EUFOREA Consensus Paper
J Christian Virchow1, Xander Bertels2,3, Vibeke Backer4
1Klinik für Pneumologie, Allergologie und Internistische Intensivmedizin, Department für Innere Medizin, Universitätsmedizin Rostock, Rostock, Germany.
Allergy
|June 16, 2026
Summary
Achieving disease remission is now a key goal for chronic airway diseases like asthma and rhinosinusitis. This consensus provides practical guidance for inducing and maintaining remission, moving beyond symptom control.
Area of Science:
- Respiratory Medicine
- Allergology
- Otolaryngology
Background:
- The therapeutic focus for chronic airway diseases is evolving towards disease remission, not just symptom management.
- Disease-modifying treatments like biologics and immunotherapy enable remission in severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and allergic rhinitis (AR).
Purpose of the Study:
- To establish practical, consensus-based guidance for inducing and maintaining remission in global airway diseases.
- To provide a unified approach for managing conditions previously viewed as separate comorbidities.
Main Methods:
- An international expert panel reviewed current evidence on airway disease remission.
- Consensus statements were developed through expert deliberation in Rome (October 2025).
Main Results:
- Remission is a therapeutic target applicable to all disease severities, not just severe cases.
- CRSwNP with nonallergic eosinophilic asthma and AR with allergic asthma should be viewed as manifestations of a single disease.
- Pragmatic definitions for remission are recommended, utilizing a 4-week symptom recall and a 12-month remission period.
Conclusions:
- Remission is an achievable therapeutic goal in chronic airway diseases.
- This consensus offers practical guidance to optimize patient outcomes by focusing on remission.
- Integrated subspecialty assessment is crucial for evaluating remission.
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