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Updated: Jun 18, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Risk stratification of 1-year atrial tachyarrhythmia recurrence after ablation in patients with persistent atrial

Jingcheng Chen1, Liang Zhao2, Kai Zhang3

  • 1Department of Cardiology, The Second People's Hospital of Changzhou, The Third Affiliated Hospital of Nanjing Medical University, Changzhou, 213003, China.

BMC Cardiovascular Disorders
|June 17, 2026
PubMed

Insights

A new ALADS-AF score helps predict 1-year atrial tachyarrhythmia recurrence after catheter ablation for persistent atrial fibrillation. This tool aids in patient discussions and follow-up planning for better rhythm outcomes.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Informatics

Background:

  • Atrial fibrillation (AF) is a prevalent arrhythmia in China with low treatment rates.
  • Catheter ablation (CA) is effective for AF, but recurrence is common in persistent AF (PsAF).
  • A need exists for tools to predict recurrence risk after CA.

Purpose of the Study:

  • Develop a risk stratification tool for 1-year atrial tachyarrhythmia (ATa) recurrence after de novo CA.
  • Identify key predictors of ATa recurrence in PsAF patients.
  • Create a user-friendly score for clinical application.

Main Methods:

  • Multicenter retrospective study (Jan 2015-May 2021) with 1,689 patients.
  • Patients divided into development (n=1,126) and test (n=563) cohorts.
  • Cox regression analysis used to develop the ALADS-AF score (Age, LAD, Duration of AF, Sex).

Main Results:

  • 1-year ATa recurrence rate was 26.1% in the study population.
  • Recurrence associated with older age, larger Left Atrial Diameter (LAD), longer AF duration, and female sex.
  • The ALADS-AF score demonstrated a C-index of 0.57.

Conclusions:

  • The ALADS-AF score is a simple tool for stratifying 1-year ATa recurrence risk post-CA in PsAF.
  • Facilitates pre-procedural discussions and expectation setting.
  • Supports consistent follow-up planning for patients undergoing ablation.
Abstract

Keywords:
Atrial fibrillationCatheter ablationRisk score, Risk stratification, One-year atrial tachyarrhythmia recurrence

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