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Updated: Jun 18, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
Published on: July 28, 2018
A new method for visualizing cerebrovascular vessels
Qiang Gu1, James Raymick1, Sumit Sarkar1
1Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States.
Abstract:
Studying the cerebrovasculature is crucial for both basic neuroscience and clinical medicine, as the brain's vascular network is dynamic and undergoes changes with aging and disease. In this study, we introduce a novel approach for visualizing cerebrovascular vessels. The method is simple, requires no exogenous fluorophores, and allows for multiple labeling with additional molecular markers. This method will facilitate cerebrovascular research concerning angiogenesis and remodeling associated with aging, cerebrovascular diseases, and neurodegenerative disorders.
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