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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase

Temitayo O Alegbejo Price1, Daniel G Silva1,2, Miguel M Vaidergorn1

  • 1Center for the Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.

ACS Medicinal Chemistry Letters
|June 17, 2026
PubMed

Keywords:
Nitroreductasecompound fragmentationdrug discoveryneglected tropical diseasesnitrofurantrypanosomatids

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