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Redefining lightweight vision models for healthcare AI
Linus Lee1, Zhibin Feng1, Jen Hong Tan1
1Data Science and Artificial Intelligence Lab, Singapore General Hospital, Singapore, Singapore.
Frontiers in Artificial Intelligence
|June 17, 2026
Summary
We developed ultra-lightweight medical vision transformers, MedLiT-seed and MedLiT-nano, with 2.1M and 0.75M parameters respectively. These efficient models achieve competitive performance in medical image analysis, outperforming larger architectures.
Area of Science:
- Artificial Intelligence
- Computer Vision
- Medical Imaging
Background:
- Traditional medical vision models are parameter-heavy, prompting research into architectural efficiency.
- Achieving high classification performance without sacrificing efficiency is a key challenge.
Purpose of the Study:
- Introduce MedLiT-seed (2.1M parameters) and MedLiT-nano (0.75M parameters), ultra-lightweight vision transformers.
- Enable efficient and scalable medical image analysis.
Main Methods:
- Utilized a streamlined Mixture-of-Experts (MoE) architecture with SwiGLU, grouped query attention, and depth-wise scaling.
- Pre-trained models using masked autoencoding on ImageNet and MedMNIST, followed by fine-tuning on 12 MedMNIST 2D subsets.
- Compared performance against benchmark models like ResNet, MedViT, and AutoML systems.
Main Results:
- MedLiT-seed achieved top AUC on 4 subsets and strong performance on others, outperforming models 10-20x larger.
- MedLiT-nano matched or exceeded ResNet-18 and AutoML baselines on several subsets.
- Transfer learning from ImageNet improved convergence and generalization; increasing embedding size was more impactful than increasing expert count.
Conclusions:
- MedLiT's MoE-based token routing offers a viable pathway for competitive accuracy with minimal parameters (around 2M).
- Selective computation routing through specialized experts is an effective design for compact medical vision models.
- This architecture is suitable for low-resource settings and scalable fine-tuning, though multi-label task limitations require future refinement.
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