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Updated: Jun 18, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
10:49

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

Rotavirus-associated acute gastroenteritis in children under five years: a cross-sectional study from southern Iran

Marjan Tariverdi1, Mohammad Tamaddondar2, Dariush Hooshyar3

  • 1Department of Pediatrics, Clinical Research Development Center of Children's Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Iranian Journal of Microbiology
|June 17, 2026
PubMed

Insights

Rotavirus infection affects over a third of young children with acute gastroenteritis. Rotavirus-positive cases frequently experienced severe dehydration, highlighting the need for prompt medical evaluation and care.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • Rotavirus is a leading cause of severe diarrhea in children globally.
  • Acute gastroenteritis poses a significant health burden on young children.

Purpose of the Study:

  • To determine the prevalence of rotavirus in children under five with acute gastroenteritis.
  • To characterize the clinical features associated with rotavirus infection in this age group.

Main Methods:

  • A cross-sectional study involving 301 children with acute gastroenteritis.
  • Clinical and demographic data collection, dehydration assessment.
  • Rotavirus antigen detection in stool samples using ELISA.

Main Results:

  • Rotavirus was identified in 34.6% of the children studied.
  • Rotavirus-positive children had significantly higher rates of vomiting and diarrhea.
  • Severe dehydration and need for parenteral rehydration were more common in rotavirus-positive cases.

Conclusions:

  • Rotavirus is prevalent in children with acute gastroenteritis in southern Iran.
  • Rotavirus infection is associated with increased severity of dehydration.
  • Early recognition and management of rotavirus gastroenteritis are crucial.
Abstract

Keywords:
ChildDehydrationGastroenteritisInfantPreschoolRotavirus infections

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